Exhibitor:
Association of Hungarian Inventors - MAFE Inventor and
Invention: Győző GARAB dr and István POMOZI dr: Differential
Polarization Laser Scanning Microscope |
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1.
The Invention |
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Title (maximum 1 line) Differential Polarization Laser Scanning Microscope (DP-LSM) The problem the inventor(s) wanted to solve Goal: high precision quantitative 2D and 3D microscopic
DP imaging in LSMs: DP microscopy provides
important and unique information on the anisotropy and molecular organization of
complex samples of biological and biomedical origin and in artificially
constructed materials. Description. The DP-LSM combines two advanced techniques, the
laser scanning confocal microscopy (LSM) and
differential polarization (DP) spectroscopy. With the DP attachment most LSMs can be made capable of imaging with high precision
and in real time absorbance and fluorescence detected linear and circular dichroism, linear and circular anisotropy of the emission,
linear birefringence, and the degree of polarization of fluorescence emission. Presentation. The DP-LSM contains a DP unit, using high frequency
modulation and a demodulation circuit, which is attached to a confocal LSM that uses scanning beam or scanning stage.
DP images can be displayed and stored in the same way as the ‘conventional’
images of the LSM. Fields of application DP imaging have been shown
to yield important information on the anisotropic architecture of different biomedical
and biological samples and in artificial molecular macroassemblies.
The main advantage of DP-LSM is that it combines the
advantages of two advanced techniques, the laser scanning confocal
microscopy (LSM), a technique that is widely used in biomedical imaging and
material sciences, and differential polarization (DP) spectrosocopy,
that is routinely used in dichrographs and other
instruments for the determination of the parameters of the anisotropic
architecture and molecular organization of different samples. Stage of development. Prototype
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2. The inventor (or inventors) |
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Name(s) Prof. Dr. Győző GARAB and
Dr. István POMOZI
GG has been working in the field of biophysics and
polarization spectroscopy for more than three decades in a leading Hungarian
research center; IP has over 10 years experience in vision and recognition
research and polarization optical applications in industrial environment Owner of the invention? |
3. Protection |
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Patent Status: US patent: US 6 856 391, 2005 EU patent: EP 1 334 339, 2007 Coauthored with Drs. R. Jörgens
and G. Weiss (Carl Zeiss Jena GmbH) Patent Application No. P0700635 (priority: |
4. Business intention |
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Open for (virtually) all options – depending also on
the project manager (negotiations in progress). |